Publications in peer-reviewed scientific journals

  1. The Human “Cochlear Battery” – Claudin-11 Barrier and Ion Transport Proteins in the Lateral Wall of the Cochlea. Wei Liu, Annelies Schrott-Fischer, Rudolf Glueckert, Heval Benav, and Helge Rask-Andersen. Frontiers in Molecular Neuroscience. 10 (2017). doi: 10.3389/fnmol.2017.00239
  2. Molecular composition and distribution of gap junctions in the sensory epithelium of the human cochlea—a super-resolution structured illumination microscopy (SR-SIM) study. Wei Liu, Hao Li, Fredrik Edin, Johan Brännström, Rudolf Glueckert, Annelies Schrott-Fischer, Matyas Molnar, Dirk Pacholsky, Kristian Pfaller, and Helge Rask-Andersen. Upsala Journal of Medical Sciences. (2017): 1-11. doi: 10.1080/03009734.2017.1322645
  3. Streptococcus pneumonia e -induced ototoxicity in organ of Corti explant cultures. Michael Perny, Magdalena Solyga, Denis Grandgirard, Marta Roccio, Stephen L. Leib, and Pascal Senn. Hearing Research. 350 (2017): 100-109. doi: 10.1016/j.heares.2017.04.012
  4. The effect of pulsed electric fields on the electrotactic migration of human neural progenitor cells through the involvement of intracellular calcium signaling. Hisamitsu Hayashi, Fredrik Edin, Hao Li, Wei Liu, and Helge Rask-Andersen. Brain Research. 1652 (2016): 195-203. doi: 10.1016/j.brainres.2016.09.043
  5. Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs. Will J. McLean, Dalton T. McLean, Ruth Anne Eatock, and Albert S. B. Edge. Development. (2016): dev.139840. doi: 10.1242/dev.139840
  6. Single-cell analysis delineates a trajectory toward the human early otic lineage. Megan Ealy, Daniel C. Ellwanger, Nina Kosaric, Andres P. Stapper, and Stefan Heller. Proceedings of the National Academy of Sciences. 113, no. 30 (2016): 8508-8513. doi: 10.1073/pnas.1605537113
  7. The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis. M. Perny, M. Roccio, D. Grandgirard, M. Solyga, P. Senn, and S. L. Leib. Journal of Neuroscience. 36, no. 29 (2016): 7740-7749. doi: 10.1523/JNEUROSCI.0554-16.2016
  8. Scanning Electron Microscopic Examination of the Extracellular Matrix in the Decellularized Mouse and Human Cochlea. Peter A. Santi, Robair Aldaya, Alec Brown, Shane Johnson, Tyler Stromback, Sebahattin Cureoglu, and Helge Rask-Andersen. JARO. 17, no. 3 (2016): 159-171. doi: 10.1007/s10162-016-0562-z
  9. Sox2 in the differentiation of cochlear progenitor cells. Judith S. Kempfle, Jack L. Turban, and Albert S. B. Edge. Sci Rep. 6 (2016): 23293. doi: 10.1038/srep23293
  10. Strategy towards independent electrical stimulation from cochlear implants: Guided auditory neuron growth on topographically modified nanocrystalline diamond. Yixiao Cai, Fredrik Edin, Zhe Jin, Andrei Alexsson, Olafur Gudjonsson, Wei Liu, Helge Rask-Andersen, Mikael Karlsson, and Hao Li. Acta Biomaterialia. 31 (2016): 211-220. doi: 10.1016/j.actbio.2015.11.021
  11. 3D computational reconstruction of tissues with hollow spherical morphologies using single-cell gene expression data. Robert Durruthy-Durruthy, Assaf Gottlieb, and Stefan Heller. Nat Protoc. 10, no. 3 (2015): 459-474. doi: 10.1038/nprot.2015.022
  12. Cell cycle reactivation of cochlear progenitor cells in neonatal FUCCI mice by a GSK3 small molecule inhibitor. M. Roccio, S. Hahnewald, M. Perny, and P. Senn. Sci Rep. 5 (2015): 17886. doi: 10.1038/srep17886
  13. Inner Ear Hair Cell-Like Cells from Human Embryonic Stem Cells. Mohammad Ronaghi, Marjan Nasr, Megan Ealy, Robert Durruthy-Durruthy, Joerg Waldhaus, Giovanni H. Diaz, Lydia-Marie Joubert, Kazuo Oshima, and Stefan Heller. Stem Cells and Development. 23, no. 11 (2014): 1275-1284. doi: 10.1089/scd.2014.0033

Other public documents

  1. Project leaflet. This leaflet explains the general OTOSTEM concept. Download the leaflet
  2. 1st Publishable Summary. A summary of the achievements of the first 18 months. Download the 1st publishable summary
  3. 2nd Publishable Summary. A summary of the achievements up to October 2016 (project month 36). Download the 2nd publishable summary

The OTOSTEM project has received funding from the European Community's Seventh Framework Programme under grant agreement No. 603029.